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DESCRIPTION:Tuning the brain: Understanding non-invasive brain stimulation 
 via electrophysiology and coupled oscillators\n\nMatthew Krause\, º£½ÇÉçÇø U
 niversity\n	Tuesday February 24\, 12-1pm\n	Zoom Link: https://mcgill.zoom.us
 /j/87078928687\n	In Person: 550 Sherbrooke\, Room 189\n	\n	Abstract: Transcra
 nial Electrical Stimulation (tES) is the oldest yet least understood form 
 of brain stimulation. The technique itself is simple: weak electrical curr
 ents are applied to the head in the hopes of altering brain activity and\,
  in turn\, behaviour. Over the last two thousand years(!)\, various groups
  have reported that tES causes striking improvements in cognition and dise
 ase symptoms. Yet these results are frustratingly difficult to replicate\,
  leaving a fundamental question unanswered: does tES meaningfully alter ne
 ural activity at all?\n\nHere\, we directly address this question by recor
 ding the activity of individual neurons in macaque monkeys receiving tES\,
  allowing us to probe how stimulation affects single cells\, neural circui
 ts\, and behaviour under translationally-relevant conditions. We find that
  tES does shape brain activity — but its effects are complex and strongly 
 shaped by the brain's own dynamics. Identical stimulation parameters can p
 roduce categorically different effects depending on brain state. I will sh
 ow how coupled oscillator models capture this phenomenon and argue that th
 is framework will ultimately enable us to design simple tES interventions 
 that selectively enhance or suppress brain oscillations involved in neurop
 sychiatric disease.\n
DTSTART:20260224T170000Z
DTEND:20260224T180000Z
SUMMARY:QLS Seminar Series - Matthew Krause
URL:/qls/channels/event/qls-seminar-series-matthew-kra
 use-371313
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