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Standard Operating Procedures (SOPs) provide a detailed description of commonly used procedures.

Note that the use of the words ‘should’ and ‘must’ in these SOPs is consistent with their defined use in Canadian Council on Animal Care (CCAC) guidelines. The term 'should' indicates an obligation, for which any exceptions must be justified to, and approved by, an Animal Care Committee. The term 'must' indicates a mandatory requirement.

Any deviation from the approved procedures must be clearly described and justified in the Animal Use Protocol application in AMS. Approval of the protocol indicates approval of the deviation from the SOP for that project only.

The following Standard Operating Procedures (SOPs) were created and/or revised by the Veterinary Committee and approved by the Animal Policy and Welfare Oversight Committee (APWOC).

If you have questions or have a recommendation to make, please send an animalcare [at] mcgill.ca (email) or talk to the Veterinarian in your area.

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SOPs

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Controlled Substances

SOP 401 on Cannabis and Controlled Substances.

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SOP 101-Rodent Analgesia	SOP 107-Bird Analgesia
SOP 102-Rabbit Analgesia	SOP 108-Fish Aquatic Amphibian Reptile Analgesia
SOP 103-NHP Analgesia	SOP 109-Ruminant Analgesia
SOP 105-Cat Analgesia	SOP 122-Ferret Analgesia
SOP 106-Swine Analgesia	Ìý

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ÌýSOP 110 - Mouse Anesthesia	ÌýSOP 118 - Fish and Aquatic Amphibian Anesthesia
ÌýSOP 111 - Rat Anesthesia	ÌýSOP 119 - Swine Anesthesia
ÌýSOP 115 - NHP Anesthesia	ÌýSOP 120 - Rodent Anesthesia Protocol Lung Physiology Measurements
ÌýSOP 117 - Cat Anesthesia	ÌýSOP 121 - Bird Anesthesia

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ÌýSOP 201 - Rodent Surgery	SOP 205 - Rodent Tumor Resection
ÌýSOP 202 - Rodent Stereotaxic Surgery	SOP 206 - Rodent Ovariectomy
ÌýSOP 203 - Large Animal Surgery	SOP 207 - Rodent Castration
ÌýSOP 204 - Xenopus Egg and Oocyte Collection	SOP 208 - Rodent Mammary Fat Pad Injection

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ÌýSOP 301 - Rodent Euthanasia	ÌýSOP 304 - Avian Euthanasia
ÌýSOP 302 - Large Animal Euthanasia	ÌýSOP 305 - Transcardiac Perfusion
ÌýSOP 303 - Fish and Aquatic Amphibian Euthanasia	Ìý

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Ìýº£½ÇÉçÇø's EHS SOP 401 - Controlled Substances	ÌýSOP 410 - Humane Intervention Points
ÌýSOP 402 - Tissue Collection for Genotyping - Mice	ÌýSOP 412 - Humane Intervention Points for Aging Rodents
ÌýSOP 403 - Guidelines Blood Collection Volumes and Frequency	ÌýSOP 413 - Tissue Collection for Genotyping - Rats
ÌýSOP 404 - Substance Administration	ÌýSOP 415 - Humane Intervention Points for Rodent Cancer Models
ÌýSOP 405 - Monoclonal Antibody Production - Mice	SOP 417 - Food and Water Restriction in Rodents
ÌýSOP 406 - Polyclonal Antibody Production - Rabbits	SOP 418 - Humane Intervention Points for Animals Used in Training
ÌýSOP 407 - Polyclonal Antibody Production - Rats	SOP 419 - Humane Intervention Points for Rodents Models Involving Paralysis
SOP 409 - Maintaining Clinical Records	SOP 420 - Estrous Cycle Assessment in Rodents
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This Monitoring Log is to be prepared by the Facility Animal Care Committee as per the approved Animal Use Protocol: ÌýMonitoring log TEMPLATE Ìý
ÌýCMARC NHP Activity Tracking and Procedures Requiring Anesthesia Log

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ÌýSOP 501- Animal Transport and Use Outside of Animal Facilities	ÌýSOP 522 - Environmental Enrichment Program for Fish
ÌýSOP 502 - Environmental Enrichment Program for Rodents	ÌýSOP 523 -ÌýEnvironmental Enrichment Program for Amphibians
ÌýSOP 504 - Environmental Enrichment Program for Rabbits	ÌýSOP 525 - Cat Husbandry
ÌýSOP 505 - Environmental Enrichment Program for Hamsters	ÌýSOP 526 - Environmental Enrichment Program for Cats
ÌýSOP 506 - Environmental Enrichment Program for Guinea Pigs Ìý	ÌýSOP 527 - Finch Husbandry
ÌýSOP 507 - Environmental Enrichment Program for NHPs	ÌýSOP 528 - Environmental Enrichment Program for Birds
ÌýSOP 508 - Rodent Husbandry	ÌýSOP 531 - Animal Acquisition Receiving and Acclimation
ÌýSOP 513 - Marmoset Husbandry	ÌýSOP 532 - Vermin Control Program
ÌýSOP 515 - Marmoset Feeding	ÌýSOP 533 - Microbiological Monitoring Program
ÌýSOP 516Ìý- Marmoset Cage Changing Ìý	ÌýSOP 536 - Procedure Room Maintenance
ÌýSOP 517 - Marmoset Room Sanitation	ÌýSOP 537 - Working in Laminar Flow Hood or Animal Transfer Station or Biological Safety Cabinet
ÌýSOP 518 - Transportation of NHPs Between Facilities	ÌýSOP 540 - Operating Room Maintenance
ÌýSOP 519 - Aquatic Animal Husbandry	ÌýSOP 541 - Vendor Approval for Animal Feed and Bedding Suppliers
ÌýSOP 521 - Macaque Husbandry	Ìý

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ÌýSOP 601 - Veterinary Care Program	ÌýSOP 614 - Guidelines on Wire-Bottom Caging for Rodents
ÌýSOP 602 - Rodent Health Monitoring Program	ÌýSOP 615 - Rodent Irradiation
ÌýSOP 603 - Rodent Quarantine Program	ÌýSOP 616 - Rodent Identification
ÌýSOP 604 - Bioexclusion Levels for Rodents	ÌýSOP 619 - Common Rodent Treatment
ÌýSOP 605 - Rodent Import Ìý	ÌýSOP 622 - Marmoset Health Monitoring Program
ÌýSOP 606 - Reporting Concerns Regarding Animal Care and Use	ÌýSOP 623 - Marmoset Breeding Colony Management
ÌýSOP 607 - Long-term Housing	ÌýSOP 626 - Macaque Health Monitoring Program
ÌýSOP 608 - Mouse Breeding Colony Management	ÌýSOP 631 - Macaque Herpes B Testing
ÌýSOP 609 - Rat Breeding Colony Management	ÌýSOP 632 - Animal Welfare Assessment
ÌýSOP 610 - Testing of Biological Material Ìý	ÌýSOP 636 - Storage and Transport of Primate Tissues
ÌýSOP 611 - Excluded Pathogens - Rodent Facilities	ÌýSOP 637 - Cumulative Endpoints
ÌýSOP 612 - Working with Immunodeficient Mice	ÌýSOP 638 - Positive Reinforcement Training
ÌýSOP 613 - Working with Rodents in the Imaging Facility	Ìý

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ÌýSOP 701 - Macaque-Related Injury	ÌýSOP 709 - Waste Anesthetic Gas Scavenging
ÌýSOP 702 - Animal Related Injury	ÌýSOP 710 - Personal Protective Equipment Requirements
ÌýSOP 703 - Use of Viral Vectors in Neuroscience - Rodents	ÌýSOP 715 - Use of Cisplatin in Rodents
ÌýSOP 705 - Animal Containment Level 2 – Rodents	ÌýSOP 716 - Use of Doxorubicin in Rodents
ÌýSOP 706 - Use of Hazardous Agents in Rodents - General	ÌýSOP 717- Use of Tamoxifen in Rodents
ÌýSOP 708 - Use of Streptozotocin in Rodents	Ìý

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ÌýDC-101ÌýBio Security Cattle Complex	ÌýDC-602 Milk House Post-Milk Wash
ÌýDC-121 Flushing Gutters in the Dairy Barn	ÌýDC-603 Bulk Tank Sanitizing Procedure
ÌýDC-131 Environmental Monitoring and Maintenance	ÌýDC-604 Box Stall Milker Sanitization
ÌýDC-206 Box Stall Sanitation	ÌýDC-605 Preparing Cows for Milking
ÌýDC-207 Tie Stall Sanitation Ìý	ÌýDC-606 Post-Milking Procedure
ÌýDC-208 Heifer Pen_Stall Sanitation	ÌýDC-607 Milking Procedure
ÌýDC-209 Calf Pen Sanitation	ÌýDC-608 Milking Fresh Cows
ÌýDC-210 Acquisition of Dairy Cattle	ÌýDC-609 Milking Pail Cows
ÌýDC-211 Loading and Transporting Cattle	ÌýDC-610 Milking Cows with Box Stall Milker
ÌýDC-212 Handling and Moving Cattle Ìý	ÌýDC-611 Milking Staphylococcus Aureus Positive Cows
ÌýDC-215 Selecting Appropriate Stalls for Tethered Cattle	ÌýDC-612 Milking Antibiotic Treated Cows
ÌýDC-230 Environmental Enrichment Program for Dairy Cattle	ÌýDC-613 Accidental Milking Antibiotic Treated Cows into Milking System
ÌýDC-301 Body Condition Scoring for Dairy Cows	ÌýDC-614 Dry Treating Cows
ÌýDC-302 Lameness Scoring for Dairy Cows	ÌýDC-615 Milk Sampling
ÌýDC-303 Injury Scoring for Dairy Cows Ìý	ÌýDC-616 Milk Culturing
ÌýDC-304 Cleanliness Assessment for Dairy Cows	ÌýDC-617 California Mastitis Test (CMT)
ÌýDC-305 Mastitis Monitoring and Detection	ÌýDC-701 Substance Administration for Dairy Cattle
ÌýDC-306 Mastitis Treatment	ÌýDC-702 Blood Sample Collection
ÌýDC-307 Extra Teat Removal Calves	ÌýDC-712 Pre- and Post-Operative Procedures and Long-Term Care of Fistulated Cows
ÌýDC-311 Managing Downed Cattle Ìý	ÌýDC-713 Rumen Content Collection from Fistulated Cow
ÌýDC-315 Cumulative Endpoints Dairy Cattle	ÌýDC-714 Transfaunation
ÌýDC-360 Outdoor Exercise Habituation of Tie-Stall Cattle	ÌýDC-715 Controlled Internal Drug Release Silicone Device Insertion
ÌýDC-361 Outdoor Exercise of Tie-Stall Dairy Cattle	ÌýDC-A-1A Environmental Monitoring Log
ÌýDC-400 Heat Detection and Breeding	ÌýDC-A-2A Cattle Transport Decision Tree
ÌýDC-405 Pre-Partum Preparation of Dairy Cattle Ìý	ÌýDC-A-4A Heat Cycle, Signs and Conception rates of Dairy Cattle
ÌýDC-406 Post-Partum Care of Dairy Cattle	ÌýDC-A-4B Signs of Heat in Dairy Cattle
ÌýDC-407 Calving Cows-Heifers	ÌýDC-A-4C Factors Influencing Heat Detection in Dairy Cattle
ÌýDC-501 Colostrum Management	ÌýDC-A-4D Leg Band Color Legend
ÌýDC-502 Milk Replacer Preparation	ÌýDC-A-5A Colostrum Quality Readings
ÌýDC-503 Calf Identification Ìý	ÌýDC-A-5B Newborn Heifer Feeding Log
ÌýDC-504 Newborn Calf Care	ÌýDC-A-6A Herd Health Scoring Record
ÌýDC-505 Calf Care Feeding	ÌýDC-A-6B Injury Scoring Record for Dairy Cows
ÌýDC-506 Tube Feeding a Calf	ÌýDC-A-6C Lameness Scoring Record for Dairy Cows
ÌýDC-601 Milk House Pre-Milking Set Up	ÌýDC-A-6D Cleanliness Assessment Record for Dairy Cows

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ÌýPU-101 Biosecurity Poultry Unit	ÌýPU-2010 Environmental Enrichment Program for Poultry
ÌýPU-202 Environmental Management Broiler	ÌýPU-520 Poultry Euthanasia
ÌýPU-203 Broiler Barn Preparation	ÌýPU-A-0 Donald McQueen Shaver Poultry Unit Floor Plan
ÌýPU-204 Sanitation Procedure Broiler Barn	ÌýPU-A-2A Broiler Temperature Management Chart
ÌýPU-205 Manure Management Broiler	ÌýPU-A-3A Should this bird be loaded - Decision tree
ÌýPU-208 Loading and Transporting Broilers	ÌýPU-A-3B Handling Guidelines for Catching Crews
ÌýPU-209 Receiving Broiler Chicks and Poults	Ìý

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ÌýSW-2010 Environmental Enrichment Program for Swine

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